Simian James Rice (/ˈsɪmiən/; born February 24, 1974) is a former American football defensive end. He was drafted by the Arizona Cardinals third overall in the 1996 NFL Draft. He played college football at Illinois.

In his 12-year NFL career, Rice recorded 122 sacks, forced 25 fumbles, recovered 8, and intercepted 5 passes. He earned three Pro Bowl selections and earned a Super Bowl ring with the Tampa Bay Buccaneers in Super Bowl XXXVII. He has also played for the Denver Broncos, Indianapolis Colts and New York Sentinels.