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Zenith's BET Inhibitor ZEN-3694 is Currently Being Evaluated in Multiple Oncology Clinical Trials

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Message: Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
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Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
6
Payzone
Jan 25, 2023 04:48PM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
1
KOO-KOO2
Jan 26, 2023 06:12AM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
3
narmac
Jan 26, 2023 11:26AM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
3
Payzone
Jan 26, 2023 11:32AM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
1
KayakerBC
Jan 26, 2023 01:08PM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
3
KOO-KOO2
Jan 26, 2023 02:04PM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
2
tada
Jan 26, 2023 07:44PM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
1
tada
Jan 26, 2023 07:55PM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control

KOO-KOO2
Jan 27, 2023 06:59AM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control

KayakerBC
Jan 27, 2023 09:43AM

My guess is that they hope for better results by dropping the androgen-deprived therapy and adding the BET Bromodomain Inhibitor ZEN-3694.

PubMed: "BET bromodomain inhibitors block prostate cancer cell growth at least in part through c-Myc and androgen receptor (AR) suppression."

 

Koo

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Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control

KayakerBC
Jan 27, 2023 10:20AM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
1
KOO-KOO2
Jan 27, 2023 10:49AM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control

KayakerBC
Jan 27, 2023 11:18AM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
2
narmac
Jan 27, 2023 02:17PM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
3
KayakerBC
Jan 27, 2023 02:47PM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
3
tada
Jan 28, 2023 09:47PM
Icon president Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
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Nextblockbuster
Jan 29, 2023 08:24AM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
1
KayakerBC
Jan 29, 2023 09:27AM
Re: Merck's PIII Prostate trial, not the one with ZEN-3694, is halted for not showing improvement vs control
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KayakerBC
Jan 29, 2023 11:16AM
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