Geoff, The point of the 180 days is that is the STANDARD MAXIMUM amount of time. That does not mean that 180 days is REQUIRED. It is possible, though very unusual, that a response could be recieved by the FDA in a much shorter period of time than 180 days. I'm just saying let's see what comes out in early November before we declare that October was a complete bust. We only have a few more days. Best regards, -z PS. Re:"It all depends on what you do with it, eh?" Well, that's true. One can overdose on vitamin E, for example, or Beta Carotine. The announcement was that Agrastim had been approved for use, even in human applications, when used within the prescribed guidelines. In other words, "follow the directions". LOL