National Cancer Institute Definitions:
castrate-resistant prostate cancer (ZEN-3694)
Prostate cancer that keeps growing even when the amount of testosterone in the body is reduced to very low levels. Many early-stage prostate cancers need normal levels of testosterone to grow, but castrate-resistant prostate cancers do not. Also called CRPC.
hormone-sensitive prostate cancer (Failed Trial)
Prostate cancer that needs androgens (male hormones) to grow and therefore stops growing when androgens are not present. Many early-stage prostate cancers are androgen-dependent, so reducing the amount of androgens in the body or blocking their action may be an effective type of therapy. Also called androgen-dependent prostate cancer, androgen-sensitive prostate cancer, castrate-sensitive prostate cancer, CSPC, and HSPC.
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