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Zenith's BET Inhibitor ZEN-3694 is Currently Being Evaluated in Multiple Oncology Clinical Trials

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Message: Re: And we wait.....
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Jan 30, 2018 04:56PM

narmac, I believe that the newco spin off was a brilliant spin off to protect that side of the portfolio and lucky it was done and they did have a compound that showed cancer potential at that time then came the patent issue and the CEO firing (communications completely bungled by Don).

That being said Don does not show any respect to ordinary shareholders. To imply that an IPO was coming after the $10 million PP was misleading and irresponsible at best.

I believe you said you don't understand the Zen Cap and Zen Epi structure and how it might work on the revenue side. Currently I doubt that even if apabetalone started to pay royalities to Zen Cap shareholders will not see any of that money for a very long time. I have no clue how this structure will work and Don is evasive on this issue (if he even understands it).

I still hold the belief that Don thought ASSURE was going to succeed. If it had succeeded of course credibility for both companies would have been dramatically enhanced and the trial timelines for the next phase may have been quicker??? If ASSURE was a success in RCT suitors of apabetalone may have been at the door. A successful sale of apabetalone could have provided revenue for the long term journey of Zenith. It didn't happen.

Also, I am sure the Zenith scientists are working hard on the zen3694 trial but I am also becoming suspicious (because of Don) or I guess at least doubtful that the trial is going well.

From the very limited number of papers I've read on epigenetics and cancer treatments while it appears there are signs for optimism I sense it will be an extremely long journey. And yet, the Zenith scientists may discover the types of patients that zen3694 works well for and this would be a break through if it extended life expectancy and perhaps enhanced enzalutimide. But I don't have my fingers crossed yet.

Given that there are over 200 cancers perhaps epigenetics will work on one of them and this will be a game changer in terms of science and investment.

Again, like RVX, this is a confusing mess because of Don at least for me. It would be fantastic to hear directly from the scientists and get a very clear understanding of what they see in the trial.

GLTA

Toinv

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