Re: BET inhibitors promising therapy for rare pediatric brain tumor

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Zenith's BET Inhibitor ZEN-3694 is Currently Being Evaluated in Multiple Oncology Clinical Trials

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BearDownAZ

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Re: BET inhibitors promising therapy for rare pediatric brain tumor

in response to

Re: BET inhibitors promising therapy for rare pediatric brain tumor

SanFrancisco99

posted on Mar 01, 2017 12:48PM

They primarily used JQ1, but also did some follow up in vivo with I-BET 151 and in vitro with OTX-015. All pan-BET inhibitors that inhibit both bromodomains of multiple BET family proteins. They did not use any selective BET inhibitors in this paper.

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