Hartland,

My understanding is that the ZEN-3694 trial is based on a "3 + 3 Dose Escalation Design" as described in the Zenith Q2 update slide 17. Here's a previous post of mine that talked about this. Three patients started at the lowest dose back at the beginning of the trial and as each 28-day cycle is completed, the safety data is assessed and 3 more patients are added at the next highest dose level, if safety data allows. Rinse and repeat. They started dosing June 15, 2016 and each dose escalation step happens every 28 days. So my understanding is that the 28 day cycles will end July 13 (cycle 1), August 10 (cycle 2), September 7 (cycle 3), October 5 (cycle 4), November 2 (cycle 5), November 30 (cycle 6), December 28 (cycle 7). So today is the 12-week mark since start of dosing, so they should be close to starting cycle 4.

BearDownAZ