1. Apabetalone supressing chemorisistance; interesting...
"Moreover, existing studies have reported that overexpressed ABCA1 facilitates tumor cell proliferation, tumor growth, and acquired chemotherapy resistance in multiple tumors [13,14,15, 18]. Yet treatment with inhibitor apabetalone ameliorates cell proliferation, tumor progression, and chemotherapy resistance."
Drug metabolism-related gene ABCA1 augments temozolomide chemoresistance and immune infiltration abundance of M2 macrophages in glioma | European Journal of Medical Research | Full Text (biomedcentral.com)
2. BETonMACE referenced in CRM syndrome burden - Review study
Humanistic and Economic Burden of Patients with Cardiorenal Metabolic Conditions: A Systematic Review | Diabetes Therapy (springer.com)