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Message: Screening/NR Tmr morn Dosing has begun?

"Maybe Bear,CityC etc can shed some light on how long this sort of "screening" might take? I'm thinking a a few hours max , can't imagine it taking several day's given the immediate health issues/concern(s)??"


I agree. It shouldn't take long to screen. I would guesstimate 1-3 days. It can't take too long, since one of the listed inclusion criteria is 10 days or less since onset of symptoms. Assuming that most patients will have experienced symptoms for a few days before being admitted to the hospital, this coud mean that screening must move fast once admitted to hospital. I expect a news release for start of dosing in first patient(s) this week, as early as tomorrow. However, my expectations have not matched reality several times with Resverlogix's clinical programs. 

https://clinicaltrials.gov/ct2/show/NCT04894266

Inclusion Criteria:

Provide informed consent before participation in the study.

Aged ≥18 years

Hospital admission with symptoms suggestive of COVID-19 infection

Ten days or less since the onset of symptoms

Virological confirmation of SARS-CoV2 infection by reverse transcriptase PCR (RT- PCR) according to Center for Disease Control and Prevention (CDC) guidelines within the previous 72 hours

Subjects showing bilateral pulmonary infiltrates on chest imaging

Saturation of oxygen (SpO2) by pulse oximetry <94% on room air at sea level.

Female subjects must meet one of the following:

If of childbearing potential, female subjects must have a negative urine pregnancy test at screening and must also be willing to practice total abstinence or to use an approved (non-hormonal) form of birth-control throughout the study treatment phase and up to 28 days after the last study drug dose if randomized to apabetalone." -OR-

Meet at least one of the following criteria:

Be postmenopausal, defined as having been amenorrheic for at least 2 years

Have had a hysterectomy or a bilateral oophorectomy

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