jonzobot - Although I didn't read every word of the trial cost article some things just didn't add up. There was no mention of average trial size or length. Lab costs for a PII looked to be just 30% lower than a PIII. In our case BoM was about 10X's the size of the previous PII so lab costs at just 30% higher just didn't compute for me, especially since our PIII took close to 4X's longer. Also the cost to get a drug to market over the time that they did the study was around $800 million but when you looked at the estimates for the most recent time frames it is $1.3 to $1.7 billion. Those kinds of costs to get a drug to market also does not compute with me when they are saying $52 million or less for each of the PI, PII and PIII trials that are required. Even adding in a PIV at $162 million only brings a high total trial cost estimate in at $318 million which is uber conservative using their trial cost averages.

If someone with pharma experience could chime in on 1) Trial costs, 2) Costs to get a drug to market, and 3) % of trial costs versus total cost to get a drug to market I would greatly appreciate it.

tada