I don't know enough about the science to make any connection (or not) to RVX 208, other than they discuss inflamation, sugar metabolism and a whole host of other factors.  I believe RVX 208 helps reduce inflamation, and therefore this study may have some bearing on RVX.  But, I'll leave that to the experts.

excerpt:

Microglial protein markers within this module are biased toward an anti-inflammatory disease-associated state, suggesting that it reflects a protective or compensatory function in response to AD pathology. Proteins from this module are increased in cerebrospinal fluid in individuals with AD, including in the asymptomatic stage of the disease. Our results highlight the importance of inflammation, sugar metabolism, mitochondrial function, synaptic function, RNA-associated proteins and glia in the pathogenesis of AD and provide a robust framework for future proteomic and multiomic studies on AD brain and biofluid biomarkers.

https://www.nature.com/articles/s41591-020-0815-6.epdf?referrer_access_token=PpSw11ox1DlU2ftwNLXapNRgN0jAjWel9jnR3ZoTv0MBdO2tHk_vYSS2TnQUIXCt8muewWUWPIhnPlhCy_VuExZFhavF3R_fAiqZ0Kn33om78dyIKVIkaKJ-LOkhpLD03ml2qvyd6CJkn4TUo7Sk3UnpzM8PosVyxjcEpf2uPXsYnfmho-iXfrZC_iE4nn2C&tracking_referrer=www.biospace.com