NBB,

Thanks to you and rndtBL for that explanation. Interestingly, RVX is suggesting that downregulation of the ACE-2 enzyme (i.e. lessening its amount) may be beneficial (less protein for the virus to use to gain access to the cell) whereas this author is suggesting that more ACE-2 enzyme may be beneficial:

"It builds on reports from China to suggest that a mechanism of lung injury during the viral infection may be through inappropriate effects of excess free angiotensin-II protein, which is floating around out there because the ACE-2 that would normally be soaking it up is occupied by coronavirus particles. If that’s the problem, then increasing the amount of ACE-2 protein might paradoxically be just what you want to do to restore some balance to the angiotensin system. In that case administering more angiotensin receptor antagonists would be an effective way to upregulate the production of ACE-2."

Well, shall we place our bets:  more or less is better?

Jupe