Re: Recent findings point to BET protein and ACE2 inhibition as possible means to slow and reduce the impact of COVID-19....
posted on
Mar 23, 2020 07:20PM
Thanks Jonzo!
Hadn't seen that one before.
Here back at you
re: rvx-297
http://molpharm.aspetjournals.org/content/92/6/694
" RVX-297 suppressed EAE pathology when administered to mice either prophylactically or therapeutically. In addition, the production of multiple cytokines in vivo (Fig. 7) and ex vivo (Table 6) was suppressed by RVX-297. In vivo efficacy was comparable or superior to that of the S1P1 agonist FTY720 (fingolimod), an approved therapeutic agent for the treatment of MS."