Re: FDA grants Fast Track designation to Jardiance for the treatment of CKD

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BearDownAZ

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Re: FDA grants Fast Track designation to Jardiance for the treatment of CKD

in response to

Re: FDA grants Fast Track designation to Jardiance for the treatment of CKD

iconoclast

posted on Mar 15, 2020 10:22AM

Iconoclast,

I am just highlighting the good news for Jardiance, which is an SGLT2 inhibitor. This class of drugs was shown to synergize with apabetalone in BETonMACE for cardio benefit, including heart failure. SGLT2 inhibitors have previously shown their own cardio benefit (i.e. EMPA-REG OUTCOME) for 3-point MACE. Additionally, SGLT2 inhibitors are showing some benefit for heart failure and CKD too. Since apabetalone is being developed for these same indications, AND because apabetalone seems to synergize with SGLT2 inhibitors, I was just bringing this news to light. That is all.