"Sorry, Bear, you’ve lost me. What do you mean by 2 and 4 point chages?"

I'm talking about MoCA score changes vs. basline and vs. placebo.

Look at the data (slides 4, 5 and 6): http://118009.choruscall.com/resverlogix/resverlogix20191206.pdf

Also posted here: https://twitter.com/BearDownAZ_2019/status/1202958960220917760?s=20

There is apabetalone improvement vs. baseline and vs. placebo in the subgroup with baseline MoCA <22. The apabetalone treated patients went from average of ~18 MoCA score at baseline to ~20 MoCA score at 52 weeks and ~22 MoCA score at end of study. Placebo group paralled the improvement at 52 weeks (going from about 18 MoCA score at baseline to 20 MoCA score at one year), but then the apabetalone group diverged from placebo and continued to improve by about another 2 MoCA score points by end of study for a MoCA score difference of about 2 MoCA score points by end of study vs. placebo and about 4 MoCA score points by end of study vs. baseline.

BDAZ