Nice post Jonzobot. About your point #2.....correct, we don't know if that headline refers to all ~469 70+ year old patients in the cognition sub-study, or the pre-specified sub-group of those w/ baseline MoCA <26 (~246 patients) or the pre-specified sug-group of those w/ baseline MoCA <21 (~85 patients).

Also keep in mind that in addition to the general MoCA score (30 point composite), there are 7 individual domains that contribrute to the total potential score of 30: Visuospatial/Executive Function, Naming, Attention (Digits, Letters, Subtraction), Language (Repetition, Fluency), Abstraction, Memory (Recall), Orientation. The data presented this week will very likely not just show the total MoCA but the contribution of the individual compenents as well.

https://www.resverlogix.com/upload/event/42/4388386bbd26/2019-03-29---ad-pd-2019-cummings-final.pdf

https://www.resverlogix.com/upload/media_element/173/b9738b92dd21/2019-07-08---aaic-poster-2019-final.pdf