Combine:  did not meet the rigorous academic requirements in confirming the primary endpoint.

With: Apabetalone has now confirmed a safety profile worthy of a chronic use drug.  I believe future released data will confirm this drug works.

Put those two statements together and there is reason for some optimism.  If Don's belief is right, then the question is...works as what?  A CVD drug?  CKD?  Cognitive Dementia?  All three?