Not to push the point, because I understand the possibility of combining the 4 trials for a postiive outcome provides a slim hope at best on the primary outcome.....I'm just wondering to what degree they missed the "rigorous academic requirements"...if it was by such a slim margin that perhaps 8 narrowly defined 3 point MAC events could tip the scale.

Looking for some manna from heaven perhaps....40 years wandering in the desert, 40 days of rainy weather, 40 days fasting and being tempted.