There is no requisite that the company initiate the change. That passage just explains the situation should the company initiate the change. The first sentence just refers to a change and the second goes into explaining should the company have initiated it. I believe this is totally pertinenent to the RVX situation. This section refers you with the link "1" to what is below. I think it is safe to say that TLD release could have a significant effect on the market price.
Securities legislation defines the term material change as "a change in the business, operations or capital of the issuer that would reasonably be expected to have a significant effect on the market price or value of any of the securities of the issuer