Its simply info, you can do with it as you wish...much like any other info we have.  

One commonly held belief is that today's short sellers are tomorrow's buyers...while I think that's more true with long established and profitable companies, in Resverlogix's case I believe it will also apply if BETonMACE succeeds obviously.  With BETonMACE success there is conceivably built in demand for 500K+ shares.  Of course some of that short interest may involve players holding warrants to mitigate risk factors.