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Re: PAH Plans get a write up in Pulmonary Hypertension News
""However, neither siRNA nor JQ1 can be used in the clinic." (my bolding)Anyone know what they mean by this? I thought JQ1 was still being tested."
JQ1 has too short of a half life and has never advanced into the clinic due to its sub-optimal pharmacokinetic properties. It is a widely used pre-clinical pan-BET inhibitor.
