Revisiting Cabel's calculation:

A previous post by Tundup states on June 21, 2018 there are 2400 patient years(as reported by RVX or an executive in informal conversation), and accumulating @210 per month.

In March 2019 there are 1900+ patients so, the accumulation rate is 155 (approx.)/month

Assuming accumulation from 210 to 155 is linear then conservative decay rate 7 /month approx.

4045 patient years

4045/2 = 2022.5 patient years for placebo group (approx) or 20.225 100-patient years

Assuming MACE rate 6.8 for placebo group; 137.53 MACE events or RRR of 18.22%

Assuming MACE rate 7.0 for placebo group; 141.575 MACE events or RRR of 23.42%

Assuming MACE rate 7.2 for placebo group; 145.62 MACE events or RRR of 28.32%

Assuming MACE rate 7.4 for placebo group; 149.665 MACE events or RRR of 32.96%

Assuming MACE rate 7.6 for placebo group; 153.71 MACE events or RRR of 37.36%

Assuming MACE rate 7.8 for placebo group; 157.78 MACE events or RRR of 41.53%

Assuming MACE rate 8.0 for placebo group; 161.80 MACE events or RRR of 45.49%