Pomp,

I commend you for your attention to detail. Great point about accounting for patient drop outs and for those already experiencing a MACE. First criticism is that it should be listed as patient "years" not "hours." Second criticism is that we don't have a solid time stamp for the numbers provided in Tundup's post or the AGM. We know the date of the post and the date of the AGM, but do not know when the conversation or data cut-off happened. So these data point may be older than listed.

I think everyone agrees that we are closing in on 250 events. But we will never get pin point accuracy using the crude estimates that we are throwing around. At the AGM and BIO-Europe it was stated "last dosing still expected in late 2018." Last dosing occurs when BETonMACE hits 250 events. The use of "expected" and "late" mean that there is a good chance we roll over into 2019. So 250 events/last dosing could be December 2018. Or it could be January 2019. Your figures are consistent with that range. 

As for your other comment, you could be right that it is a combination of seasonal pattern with the current number patient hours projected with remaining patients. Either way, we're closing in on 250 with each passing day. I think we're both in agreement that we'll hit 250 in the next 2 months.

Can you please tell us what your goal is?

Thanks for the great discussion,

BearDownAZ