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REDUCE-IT: Mixed bag. Great results for Vascepa, including 26% RRR in 3-point MACE. Substantial concern of harmful placebo effect confounds data interpretation.
CIRT: No statistically significant effect on 3-point MACE by low dose methotrexate
DECLARE-TIMI 58: Dapagliflozin no statistically significant effect on 3-point MACE
