fouremm - Short answer is, I don't have a clue. I simply used the info from the Zen/RVX update I posted 31 Jan 2018 at 4pm. I did cross check those numbers with BDAZ's estimate of 188 events and completion of 250 events. They all came out almost identical to what BDAZ came up with and company guidance. I make no claim what's so ever to being a statistician. There are a couple of statisticians that follow this board which I think could more accurately answer your question. When I did the numbers like you fouremm I came up with 6.575 man years/patient years per day, 2400 divided by 365 X 30 which would be about 197 per month. I'm as curious to hear a reasonable answer as you are.

tada