Imagine that.....a drug (RVX-208/apabetalone) already shown to be safe in Phase 1, 2 and 3 clinical trials, could offer a means to wake up HIV from latency to assist in its eradication and potentially circumvent the need for lifelong anti-retroviral theapy.
"In summary, we initially provide strong evidence that RVX-208 and PFI-1 are attractive potential candidates for HIV-1 cure studies. Our study in combination with previous reports suggests that BET inhibitors represent a group of leading compounds for combating HIV-1 latency for viral eradication and need further study."
