SanFran,

Not knowing whether we've hit 125 events yet and not knowing status of enrollment really makes it difficult to project when we may hit 175. Enrollment really seemed to slow down in H2 2017, which doesn't help us get to the target any faster.

However, based on my previous estimates based on the EXAMINE trial population, an overall increase in event rate due to the additional low-HDL requirement, and the 30% RRR in the apabetalone arm......I originally projected hitting 125 events by end of Sept 2017. If I gaze into the crystal ball for 175 events, I see early Q1 2018. But like I said, too many unknowns to trust the crystal ball too much.

BearDownAZ