I read your thoughts previously Bear....and I would welcome anyone to share their speculation as well.

Speculation is all well and good, its what we live on here a lot of the time....but obviously the devil is always in the details and it would good to know the hard facts.  If, as you suspect they will be required to increase the number of patients, with the possibility of that leading to a need to have more than 250 events and a longer time line....then shouldn't we be told?  The adjustments have been agreed to according to the PR, so there's nothing left to settle. 

According to clinicaltrials.gov there's been no updates since July of last year:

https://clinicaltrials.gov/ct2/show/NCT02586155