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Message: Re: PNH Trial?
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Jun 30, 2017 12:59PM
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Jun 30, 2017 02:19PM
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Jul 01, 2017 02:34AM

Jul 01, 2017 04:44PM
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Jul 01, 2017 04:50PM
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Jul 05, 2017 05:20PM

Tada, 

I don't think that apabetalone is C3 specific, but has broad effects on the complement cascade. See the recent published paper. It should be open access or see the NCBI link below. Also, great post on fibrosis BKC! 

Downregulation of the Complement Cascade In Vitro, in Mice and in Patients with Cardiovascular Disease by the BET Protein Inhibitor Apabetalone (RVX-208).

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Jul 05, 2017 05:50PM
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Jul 05, 2017 08:12PM
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