SanFran....the original message on the post titled futility analysis...it was started by you....and in it you referenced the fact that BetOnMACE is an event based trial with the benchmark being 250 mace events....and you further posted that the futility analysis will take place at the midway point, or after 125 events....Assuming your original post to be correct that means there is no schedule....its like baseball and 3 outs, they happen when they happen....and the longer it takes the better from my POV