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Message: Epigenetics of Aging and Alzheimer’s Disease: (RVX-208 Mentioned)

A little light reading for those with scientific minds and lots of free time: This was published December 21, 2015

file:///C:/Users/MACS%20USER/Downloads/ijms-16-26236.pdf

Small molecule inhibitors to chromatin-associated proteins: DOT1L histone methyltransferase inhibitors: EPZ004777, EPZ-5676, SGC0946; EZH2 histone methyltransferase inhibitors: GSK126, GSK343, EPZ005687, EPZ-6438, EI1, UNC1999; G9A histone methyltransferase inhibitors: BIX1294, UNC0321, UNC0638, NC0642, BRD4770; PRMT3 histone methyltransferase inhibitors: 14u; PRMT4 (CARM1) histone methyltranferase inhibitors: 17b, MethylGene; LSD1 histone demethylase inhibitors: Tranylcypromine, ORY-1001; BET histone demethylase inhibitors: JQ1, IBET762, IBET151, PFI-1; BAZ2B histone demethylase inhibitors: GSK2801; L3MBTL1 chromodomain inhibitors: UNC669; L3MBTL3 chromodomain: UNC1215; Bromodomain inhibitors: LP99, RVX-208; Chromodomain inhibito

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