Dr. Nonaka is a native Japanese citizen from Yokohama City, educated and trained as a physician and researcher both in Japan and the United States. He received M. D. from Jikei University School of Medicine in Tokyo, and Ph.D. from the Faculty of Medicine at University of Tokyo. He completed his post-doctoral fellowship at the Scripps Research Institute in La Jolla, California. Then he became Assistant Professor of the Department of Immunology at University of Tokyo. After receiving his Ph.D. degree, he returned to the United States to continue his research in the allergy and immunology field.

Since then Dr. Nonaka acquired a vast amount of experience and expertise both in medicine and business. He is Founding President of the La Jolla Institute for Allergy and Immunology (LIAI) in La Jolla, California, where he raised the largest single funding in the Southern California’s basic biomedical research history in the 1980s – more than $50 million. Today LIAI has over 430 employees and has become one of the top immunology research organizations in the United States. A survey conducted by The Scientist magazine in 2012 ranked LIAI as one of ten best places in the world to work for a postdoctoral researcher.

Dr. Nonaka started Medical Technology Applications, Inc. (MTA) as a provider of "Turn-Key Venture Realizing Services for Technology." It has been providing highly specialized and responsive analysis, advice and consulting services in the industry areas such as biotechnology, healthcare, pharmaceuticals, functional medical materials, computers and electronics, and defense technology conversion. Its service network is at an international level, especially between the United States, Japan and South East Asia. Since its formation MTA has arranged more than $160 million of financing for various high-tech and biotech companies. Dr. Nonaka has founded several venture companies in the fields such as broadband laser communications technology, vaccine technology, gene therapy, and medical devices. Dr. Nonaka is Adjunct Professor of Medicine at St. Marianna University School of Medicine in Japan, and Advisor for the RIKEN, which is the largest national science research institute of Japan.

Mr. Brule comes to Crossflo Systems with 25 years of experience in high-tech startups. He joined Crosslfo as part of the acquisition of the Vigilys product line from Kratos Defense and Security Solutions. Mr. Brule joined the Vigilys team at Kratos as the Director of Engineering and Director of Product Marketing, and led the effort to bring the product to market.

Prior to that, Mr. Brule was CTO of Osmose Utilities Services, a provider of software and services to the electric utility and telecommunications industries. He led the development and deployment of FastGate, a software system that combined handheld and server-based components for the collection of data and improved reliability of distribution networks. The FastGate product line came to Osmose when the acquired Coherent Networks, a high-tech startup that Mr. Brule helped co-found in the late 80’s. At various times through the 80’s and 90’s, he led the product development and professional services organizations at Coherent Networks, helping build it into a profitable software and services company.

Mr. Brule earned a B.S. in Computer Science and an M.S. in Computer Science and Mathematics from Syracuse University.